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Pulmonary Hypertension

Raised pressure in the Pulmonary Artery (Pulmonary Hypertension) is now recognised to impose a major global burden of disease worldwide. 

Understanding the basic mechanisms involved in the causes of different forms of the disease is of crucial importance in evolving new strategies for prevention and treatment.

The Vascular Biology Group at the Heart Science Institute have been deeply involved in defining the role of the different cells and mediators found in the lung and elsewhere in the body to understand the role they play in the causation of these diseases. The availability of human tissue from the Harefield Heart Biobank and the active transplant programme of hearts and lungs has provided a vital source for implementing these studies.

Adrian Chester and his team have continued to develop complex techniques over a period of thirty years, collaborating with national and international research groups, working to understand Pulmonary Hypertension.